2014年1月25日星期六

What causes elevation of blood pressure in CKD

Elevation of blood pressure often follows patients with CKD. If elevation of blood pressure continues very seriously, the blood is forced against the blood vessels and extra fluid in the body increases the amount of fluid in blood vessels and makes blood pressure higher. The high blood pressure can cause many diseases and affect the kidney function in turn, which is very harmful. And the more serious CKD is, the higher blood pressure is. Then you may ask why and what causes this phenomenon. Here we will make a detailed introduction for you, hoping it can be useful to you.
CKD affects high blood pressure
Elevation of blood pressure is one of the most main symptoms of CKD.
There are two ways leading to high blood pressure in CKD.
Firstly, glomerular filtration rate of patients with CKD decreases, and the absorption of sodium through kidney tubules increases, which leads to water and sodium retention. As blood volume expands, blood pressure elevates.
Secondly, renin secretion and angiotensin Ⅱ synthesis can increase in CKD. AngiotensinⅡcan make blood vessel shrink, leading to high blood pressure and stimulating aldosterone secretion. Finally water and sodium retention will increase, so high blood pressure occurs.
So we can know that the water and sodium retention is the leading cause of elevation of blood pressure.
High blood pressure affects CKD
Besides, the kidneys play a key role in keeping a person's blood pressure in a healthy range, and blood pressure, in turn, can affect the health of the kidneys. High blood pressure, also called hypertension, can damage the kidneys and lead to chronic kidney disease, too.
High blood pressure makes the heart work harder and, over time, can damage blood vessels throughout the body. If the blood vessels in the kidneys are damaged, they may stop removing wastes and extra fluid from the body. The extra fluid in the blood vessels may then raise blood pressure even more. It's a dangerous cycle.
From the clinical research, we can find that the more serious the kidney is, the higher blood pressure is. CKD relates to blood pressure with each other closely.

Above is the introduction we do for you, which can be helpful to you. If you have any question, please contact us freely by email or phone.

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