1. Patients with renal insufficiency: diabetic nephropathy patients appear kidney damage can lead to urinary protein leakage and glomerular filtration rate decline and severe hypoproteinemia, which may cause double lower limbs, eyelid and facial edema, serious person can appear systemic edema.
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2 complicated with heart disease: Patients with diabetic nephropathy (DN) is a common complication of cardiovascular disease, such as coronary heart disease, cardiomyopathy, serious illness can be due to heart function not to cause body circulatory stasis and sodium and water retention, leading to neck vein engorgement, hepatosplenomegaly and double lower limb symmetry edema.
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3. Combined with peripheral neuropathy: peripheral neuropathy in patients with diabetic nephropathy, causing peripheral vascular dilatation and congestion, double lower limbs venous congestion edema, in addition the neurotrophic disorders caused local capillary permeability increase, resulting in lower extremity edema.
4 patients with lower extremity vascular disease: when patients with lower extremity venous disease, resulting in venous reflux obstruction caused by venous hypertension, can appear lower limb edema, but often unilateral edema.
5 severe malnutrition: some patients with diabetes, due to the long-term diet, heat and protein intake is a serious shortage, resulting in low blood protein and nutrition is not benign.
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