The Latest Treatment for IgA Nephropathy--Stem Cell Transplantation

With the rapid development of biological cytology and the great national support for technology of stem cells transplantation, stem cells are playing a more and more significant role in medical treatment. At present, stem cells transplantation is the latest way to treat IgA Nephropathy and its curative effects are quite noticeable.
As we know, IgA Nephropathy is characterized by short latent period and repeating appearance. It is a special kind of glomerulonephritis which always appears after an infection in upper respiratory tract. What’s worse, the process of IgA Nephropathy is usually a chronic one, and almost half of the sufferers may have Chronic Renal Insufficiency along with the gradual development.
Nowadays there is no effective treatment for IgA Nephropathy in western medicine. Essentially speaking, IgA nephropathy is characterized by deposition of the IgA antibody in the glomerulus, so renal tissues are damaged and urinary protein and occult blood are lost along with urine. Therefore, if we want to decrease the urinary protein and occult blood, we should repair damaged renal tissues first, that is to say, repair the intrinsic cells in kidney, and then the normal function of kidney can be regained.
Let’s take a look at the latest treatment for IgA Nephropathy--- stem cell transplantation. Stem cells are infused into human body first, and then direct at renal focus to repair the damaged intrinsic cells and remit the ischemia and anoxia in kidneys, thus extending blood vessels, improving the microcirculation around kidneys, increasing the effective perfusion, repairing the focal metabolism, and preventing the further damage to kidneys to effectively control the condition. Meanwhile, stem cells can regulate the phenotypic conversion of renal cells, repair damaged cells gradually and prevent the changes of extracellular matrix so as to slower and stop the process of glomerulosclerosis and fibrosis of tubular mesenchyme, resulting in the improvement of renal functions. At the same time, the digestive circulation is ameliorated, so the patients can have a better appetite and digestion, and then the body immunity can be strengthened.

Stem cell transplantation is the latest treatment for IgA Nephropathy and is proved to have an obvious effect in clinic. Urinary protein and occult blood disappear gradually and renal function can be restored to a great extend after the transplantation.