How does Henoch-Schonlein Purpura Nephritis Cause Kidney Failure

Henoch-Schonlein Purpura Nephritis Causes Kidney Failure if left uncontrolled. This article mainly explain how Henoch-Schonlein Purpura Nephritis Causes Kidney Failure and knowing about this is helpful for us to choose treatment.
Diagnosis of Henoch-Schonlein Purpura Nephritis is based on mesangial proliferation of glomeruli. With Henoch-Schonlein Purpura Nephritis, IgA and some immune complexes can be detected in mesangial area. IgA and immune complexes release inflammatory factor which stimulate our kidney and thus causes inflammatory reaction.
Inflammatory reaction is a kind of self-protective reaction, through which, inflammatory reaction can be removed effectively. However, if our immune system is abnormal, inflammatory reaction will last and becomes more and more intense. Usually, when immoderate inflammatory reaction causes damage our own renal functional cells, which impair our kidney function. Usually, when kidney damages are caused by Henoch-Schonlein Purpura, Henoch-Schonlein Purpura Nephritis appears. With no effective treatment, more and more renal functional cells, kidney functions becomes poorer and poorer and finally, kidney failure appears.
Kidney failure is the end consequence of Henoch-Schonlein Purpura Nephritis and it appears when kidneys are totally failed. However, not everyone with Henoch-Schonlein Purpura will certainly suffer from Henoch-Schonlein Purpura Nephritis. For Henoch-Schonlein Purpura patients, if they get their disease controlled timely and effectively, kidney damages can be avoided and obviously, kidney failure can be avoided.
When Henoch-Schonlein Purpura Nephritis is diagnosed, many patients adopt hormone medications as their treatment. However, hormone medications only help to remove symptoms, and they can not remove IgA and immune complexes. Immune complexes are the root causes of kidney damages, so as long as them exist in kidney, new kidney damages will be caused and Henoch-Schonlein Purpura patients eventually run to kidney failure.
At present, only Immunotherapy is effective in removing immune complexes and IgA. Through this treatment, Henoch-Schonlein Purpura patients can be brought under control effectively and consequently, Henoch-Schonlein Purpura Nephritis stop developing to kidney failure.

How To Control HSP Nephritis Effectively

Large amounts of clinical cases found that HSP Nephritis is hard to bring under control and even if it is stopped sometimes, it relapses again. Why is this? How to control HSP Nephritis effectively?
HSP Nephritis is a kind of kidney problem which occurs because IgA or IgM circulate immune complexes deposit in kidneys and cause inflammatory immune response. Inflammatory immune response is a method that our body fight against pathogenic foreign body. Thereby, it is good to our body to some extend. However, when this response becomes extremely serious and uncontrolled, our own tissues or organs will be damaged. HSP Nephritis is a kind of kind of progressive loose of kidney function because of immoderate inflammatory immune response. Therefore, if we want to control HSP Nephritis, we must clear IgA or IgM immune complexes away from the blood as well as from the kidney. Only in this way, can we bring HSP Nephritis under control effectively.
Conventional treatment for HSP Nephritis is immunosuppressive medicines which can stop HSP kidney disease effectively and immediately, but it can not normalize all the related tests like proteinuria. Immunosuppressive medicines fail to do this just because they just block inflammatory immune response and have nothing to do with clearing IgA or IgM immune complexes away from patient's body.
Immunotherapy is a brand-new medical treatment for HSP Nephritis. This treatment is divided into six steps to control HSP Nephritis, and one of the steps focuses on removing immune complexes. Immune complexes in HSP Nephritis patient's body includes immune complexes depositing in kidney and immune complexes circulating in the blood. For these that circulate in the blood, varies blood purification technics like plasma exchange are applied to remove them and for these that depositing in kidneys, Micro-Chinese Medicine Osmotherapy is selected to clear them away.
Through combining different treatments and medical technics, immune complexes in HSP Nephritis patient's body can be cleared away. No IgA or IgM immune complexes, no inflammatory immune response and also no further kidney damages. As long as root cause of kidney damages is removed, HSP Nephritis is controlled effectively.