2012年12月24日星期一

Can I Receive Kidney Transplant with IgA Nephropathy

Many IgA Nephropathy patients choose kidney failure when their kidneys are totally failed. Kidney transplant is one of the traditional medical methods to deal with kidney failure.Kidney transplant is helpful, but actually not everyone with kidney failure can have a successful transplantation.
Kidney transplant is a medical procedure in which a kidney is put into patient's body to replace the damaged kidney work. We know kidneys are responsible for discharging wastes and when a healthy kidney is put into patient's body, it helps to clean blood. Therefore, kidney transplant is helpful. However, as IgA Nephropathy has a high reoccurrence rate after kidney transplant, IgA Nephropathy patients have a high risk to suffer from kidney problem again after kidney transplant. Therefore, it is of great importance for IgA Nephropathy patients to find an alternative treatment.
IgA Nephropathy is an autoimmune disease and marked by excessive IgA or IgA immune complexes in mesangial area. These substances do not belong to our kidney, so when they deposit in this area, inflammation occurs. Inflammation damage our kidney tissues directly, so many patients are prescribed immunosuppressive agents or hormone related medicines to block inflammation. However, as IgA or IgA immune complexes are not cleared away at all, inflammation occurs again once patients stop taking medicines or once they reduce the dose.
As many patients do not know how to treat IgA Nephropathy fundamentally,their disease can not be stopped effectively. Consequently, IgA Nephropathy progressive to kidney failure and patients have to prepare for kidney transplant. Actually, as long as they clear IgA and IgA immune complexes away from mesangial area, inflammation can be prevented and also no further kidney damages are caused. Immunotherapy is just such a method which can help to remove immune complexes from the kidney. Therefore, for IgA Nephropathy patients, if they want to avoid kidney transplant, they can have a look about Immunotherapy.

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