2013年3月22日星期五

Overview about Polycystic Kidney Disease

Just as its name implies, PKD means there are numerous cysts in kidney. Why are there cysts? What effect do the cysts have on our body? Let’s learn the basic knowledge of the PKD together!
PKD is marked by fluid collection in kidney which develop slowly in both kidneys. With the growing of the cysts, the structure of the kidney is damaged. It is a kind of single-gene hereditary disease which is divided into autosomal dominant PKD and autosomal recessive PKD. The former is more common than the latter.
Under the effect of the toxin, infection and other environmental factors, allele mutation happens to the cyst gene, resulting to epithelial cell proliferation and forming tiny polyp, blocking kidney tubules, gathering liquid. And the composition of the basilar membrane is unusual, and the adaptability of the basilar membrane is poor, then the membrane is easy to expand to the cyst. The most of the cell is changed, making the enzyme of Na+-K+-ATP which can secrete liquid plunge into the inner membrance, and the cyst increase progressively. The wall of cysts comes from any part of nephron, including proximal convoluted tubule, distal convoluted tubule and concentrated pipe.
As report goes, one patient in four who has PKD will develop into renal failure, requiring dialysis or kidney transplant to replace functions of failed kidney. Why is it?
In the early- stage of the PKD, Cysts are small in size and hardly cause influence on the blood circulation. Most people with PKD don’t know they are suffering this disease, so they miss the best opportunity for treatment. As soon as we have backache, high blood pressure, blood urine or proteinuria, we ought to go to a doctor to make comprehensive diagnosis. We should do our best to control the condition. Later, we begin to have anemia, then cysts will appear around liver and other organs. The final result is kidney function declines. At this time, we must use dialysis. Besides, we also can use micro-chinese medicine osmotherapy which can promote the blood in kidneys and enhance the flow speed of the blood. The cysts in patients can be kept in a stable condition.
PKD can not be cured completely. We can take medicine to control blood pressure, to prevent infection and to reduce pain. We also can use micro-chinese medicine to activite and support blood.
The above is a simple introduction of PKD. All the PKD patients should attach great importance to this disease

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