2013年3月19日星期二

Prognosis of Nephrotic Syndrome

Overview
It is well known that Nephrotic syndrome is charactered by the symptoms of proteinuria, edema, hyperlipidaemia, and hypoalbuminaemia. It has serious complications and must be on the differential diagnosis for any patient presenting with new-onset edema.A thorough assessment for the underlying cause of nephrotic syndrome is essential to a good prognosis.
History and symptoms
Mostly, the age is over 40 ~ 50 year old, History of hypertension is over 5 ~ 10 years. Early only night urination is increased, and then proteinuria ensues. Individual cases, due to capillary broken and can occur transient gross hematuria. But it is not with obvious lumbago,often merge arteriosclerosis retinopathy,left ventricular hypertrophy,coronary heart disease, heart failure, cerebral arteriosclerosis and cerebrovascular accident history. The course of disease is jogging along. Few of them gradually developed into kidney failure. Most of them is kidney perennial mild damage and routine urine abnormalities. The diastolic pressure of malignant hypertension should be more than 16 Kpa (120 mmHg), with obvious cardio-cerebral complications and rapid development, large proteinuria, often with hematuria, and the progressive of renal function is deceased.
Prognosis of Nephrotic Syndrome
The onset of Nephrotic Syndrome depends on the underlying cause and the causes of it varies. Some patients may have a spontaneous recovery, while others worsen despite aggressive. A number of children "outgrow" this disease in their late teens or early adulthood.
Nephrotic Syndrome is featured by relapse and recurrence. On an average, chances of recurrence or relapse of Nephrotic Syndrome is as high as 50-75%. The attacks are more frequent in the first one to two years after the Nephrotic Syndrome begins. Thus a good prognosis contributes to Nephrotic Syndrome patients.

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