How should Nephrotic syndrome patients use albumin correctly

Nephrotic syndrome patients excrete proteinuria, it easily appears hypoproteinemia, hypoproteinemia is also called protein malnutrition or edematous malnutrition. Protein is the important component of body tissue cells; protein exists in all of human body tissue cells. Physical growing and development, renewing senescent cells, repairing damaged organization are all needed protein. The indispensable component of enzyme, hormone and antibody are also protein. Protein is zwitter-ion, it has buffer function, protein controls internal body water and water distribution, and it is also body heating resource. Therefore, lack protein will cause edema and impair hormone treatment effect.
Nephrotic syndrome patients using human albumin over and over causes protein cast increase, protein cast damages kidney tubules and causes appear over and over, it will also make the recurrence rate of refractory nephrotic syndrome increase. But patients having proteinuria leads to worse hypoproteinemia, and even edema symptom, if they don’t use albumin, they can’t raise the rate of serum albumin, it will influence the effect of diuresis and detumescence. The patients often are willing to use albumin to meet the diuresis and detumescence requirements.
During nephrotic syndrome treatment, there are a lot of people often use albumin to improve protein level and reinforce treatment effect. But incorrect using albumin is not able to meet the diuresis and detumescence requirement. In a previous case, the doctor gives patient a glass of albumin every two days, it lasted half of month, but it doesn’t help to decrease the edema, and the serum protein value is the same as prior treatment. What is the reason for this result? Using venous inflow the serum protein is already excreted from kidney after one or two days, it only lasts very short term treatment. What kind of case for patients to take albumin? The decision is different under different case, as normal speaking there are two kinds of people should use albumin:
1. Severe edema patient after gets venous inflow still can’t not meet the diuresis requirement, they should use albumin. According to plasma osmotic pressure decrease leads to severe edema that is because hypoproteinemia, water in organization is not able to get into blood vessels. Using albumin improves plasma osmotic pressure and speed up the water in organization get into blood vessels to reach diuresis goal.
2. After using diuretic, patient has insufficient plasma capacity symptom, such as: hypotension, sweating, dizzy, atony and so on. Under this case patient should use albumin to improve plasma osmotic pressure level and make more organization water enter blood vessel to raise plasma capacity.
In conclusion, the above two points is not for replenishing plasma albumin, even more it is for improving plasma osmotic pressure. Furthermore, it is not good for nephrotic syndrome patients to use albumin in long term treatment. Because albumin only enhances serum albumin in short term, it can not improve fundamentally, the price of albumin is very expensive, long term using is a waste without any helpful effect. Old people or cardiac insufficiency people inflow albumin, the effective blood volume increase, it may cause the left heart failure potential risk, and the protein in urine also increases, it accelerates damage the rest of kidney cells.

Nephrotic syndrome patients should try to use fewer albumins; albumins only cure the symptoms, but not the disease. Micro-Chinese Medicine Osmotherapy just can achieve this goal in our hospital, as it is a combination of western medicines and herbal medicines.