What are Common Causes of Chronic Renal Insufficiency

If initial kidney impairment is not treated timely and properly, it will develop into chronic renal insufficiency and advanced kidney disease. What are the common causes of chronic renal insufficiency? We’ll focus on this topic in the following passage so as to help you take better preventive measures at early time.
Chronic glomerular nephritis, including IgA Nephropathy, mesangial proliferative glomerular nephritis, focal segmental glomerularsclerosis(FSGS) and mesangial proliferative glomerular nephritis.
1. Kidney diseases caused by abnormal metabolism, including diabetic nephropathy, renal vascular hypertension, renal arteriosclerosis and so on.
2. Genetic kidney diseases, such as Polycystic Kidney Disease (PKD) and Alport Syndrome. For this type of kidney disease, positive
3. Infectious kidney diseases, such as chronic pyelonephritis and renal tuberculosis.
4. Systemic diseases, such as lupus nephritis, vasculitis and multiple myeloma.
5. Obstructive kidney diseases, such as ureter obstruction and urinary tract stones.

There exist five main functional renal intrinsic cells in our body, including glomerular epithelial cells, glomerular endothelial cells, mesangial cells, tubular epithelial cells and renal interstial fibrolasts. External symptoms of renal insufficiency, such as proteinuria and hematuria, are reflections of impairment in certain renal intrinsic cell. In the deteriorating course of renal intrinsic cells, the healthy kidney cells are impaired, then severely injured and finally get totally necrotic. The necrotic cells can not be reversed by any medication. So we apply stem cell transplant so as to replenish more healthy nephrons, thus helping renal insufficiency patients improve kidney function effectively.