How Does Diabetes Cause Diabetic Nephropathy

Diabetic Nephropathy is one of the fatal complications of Diabetes. Diabetes is marked by high levels of blood sugar and kidney disease is marked by decreased GFR, so how is Diabetes related with kidney problem?
The following is the introduction that how is Diabetic Nephropathy caused. Hoping it is helpful for you.

Each kidney is made of hundreds of thousands of small units called nephrons. These structures filter your blood and help remove wastes from your body.
In people with diabetes, the nephrons thicken and slowly become scarred over time. The kidneys begin to leak and protein (albumin) passes into the urine.
Poor control of blood sugar is thought to lead to kidney damage. If you also have high blood pressure, kidney damage is even more likely.
In some cases, your family history may also play a role. Not everyone with diabetes develops this kidney problem.
People with diabetes who smoke, and those with type 1 diabetes that started before age 20 have a higher risk for kidney problems.
People of African-American, Hispanic, and American Indian origin are also more likely to have kidney damage.
Diabetic Nephropathy is caused usually after people suffer from Diabetes over 10 years, which means, the longer time that people suffer from Diabetes, the more likely that diabetics suffer from kidney problem. Therefore, for diabetics who have had high blood sugar so many years, they should take actions in advance to prevent kidney damages.