2015年8月19日星期三

Obesity Can also Cause Kidney Disease


Obesity can also cause kidney disease alert! According to statistics, a lot of obese people suffering from unclear nephritis, uremia! This is an amazing news. We know that obesity can lead to high blood pressure, high cholesterol, arteriosclerosis, fatty liver, diabetes, stroke and other diseases, but for kidney damage caused by obesity are poorly understood.
It is reported that obesity is by high blood pressure, high blood sugar (diabetes), high cholesterol, high uric acid four ways to damage the kidneys, while these four factors often influence each other, forming a vicious cycle, known medically obesity-associated nephropathy.
Obesity can cause high blood pressure, high blood pressure after kidney blood vessels will be more pressure, just like a rubber band, it takes a little stretch, but if you always high blood pressure, the rubber band will be pulled very tight. So long, blood vessels will sclerosis, kidney will harden.
Coupled with body fat, a lot of fat to whole kidney to tightly wrap the form of fat backlog, resulting in poor kidney circulation early can cause glomerular sclerosis, later there will be a whole kidney failure state, atrophy the state, resulting in the occurrence of uremia.
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Obesity prone to hyperlipidemia, causing kidney damage, its morphological changes is to increase the kidney fat content, increase the weight, volume increases; check histological findings, renal tubular glomerular basement membrane often significantly fat droplets calm, glomerular hypertrophy becomes, causing focal segmental glomerulosclerosis.
Old obese easily lead to insulin resistance, sparking occult diabetes. Especially in obese women are more non-insulin-dependent diabetes mellitus. Onset occult, atypical symptoms, usually without polydipsia, polyuria, polyphagia typical symptoms, hyperosmolar coma occurred more common occurrence is less ketoacidosis. But some patients on the surface is very robust, ruddy, energetic, seems to be ordinary people, often led by the attending symptoms of complications, kidney damage is the main complication.
High uric acid caused kidney damage. Hyperuricemia is caused due to the long purine metabolism disorders, obesity are very common. Recurrent manifestations of acute arthritis, tophi deposition, chronic arthritis and joint deformities, renal parenchymal disease and uric acid stones form.
About 20% of patients with early to 40% can be intermittent small amount of proteinuria, as the disease progresses, there may be persistent proteinuria, but also with microscopic hematuria. Urine acidic, may have mild swelling, moderate benign hypertension. Almost all of renal tubular function decreased concentration, impaired tubular concentration early in the glomerular dysfunction. The slow development of the disease often leads to kidney dysfunction and life-threatening.
Obesity can also cause kidney disease alert! Whatever effective treatment must persevere, of course, for kidney patients, diet can only play the effect of adjuvant therapy, if the condition has aggravated the trend, it is recommended to kidney hospital, take the standard treatment measures. Oh, I wish you a speedy recovery!

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