A Breakthrough in Treating Diabetic Nephropathy

Diabetic Nephropathy is one of the complications of Diabetes Mellitus which happens the most commonly in clinic, that is to say, Diabetic Nephropathy is the most serious complication of Diabetes, and also the main reason leading to end stage kidney diseases.
With the researches done in these years, stem cell transplantation is proved to be a most effective treatment for Diabetic Nephropathy, and thousands of sufferers have benefited from it already.
Diabetic Nephropathy happens when insulin is not adequate absolutely or relatively which is caused by reduced function of pancreas islet. So, in order to treat Diabetic Nephropathy, the insufficiency of cellular function should be prevented and the number of cells should be increased to save and restore the function of pancreas islet.
Stem cells are characterized by their ability of self-renewal and multi-potential in differentiation, and they are the best seed cells to renovate pancreas islet. Stem cells, especially the cord mesenchymal stem cells, can differentiate into cells which can secrete insulin, and they will still have a long-term function after many generations. Therefore, it is the most promising way for sufferers with Diabetes Mellitus to get rid of the dependence on insulin, and it may solve the traditional problem in treating Diabetes. Stem cell transplantation has many advantages in treating Diabetic Nephropathy as follows:
I. They can repair βcells in pancreas islet and help the pancreas to generate many newβcells which can secrete insulin. With the factors generated by stem cells, βcells will be renovated and proliferate more.
II. Stem cells can repair other cells that secrete insulin. There are some other cells secreting insulin in other tissues or organs in addition toβcells, through which insulin in the body can be increased in order to reduce the blood glucose.
III. By means of stem cell transplantation, the protein which conveys glucose becomes more sensitive, promoting the combination of receptors of pancreas islet and insulin so that the resistant function of insulin can be reduced.

Sufferers who receive stem cell transplant should be given professional and special nursing and further detection, relevant psychological guidance cannot be neglected either. When the sufferers have a low pressure and a right attitude towards diseases, they can recover more quickly.