The Relationship among Creatinine, Serum Creatinine and Urinary Creatinine

As for kidney disease, creatinine is the word that is paid so much attention to during the whole disease course. Also, you may hear about the serum creatinine as well as urinary creatinine. Then, what are they respectively?
Creatinine is the word that we hear about most frequently during all the process of kidney disease. It is the metabolic waste produced by the muscles in human body, and normally, there is 1mg creatinine can be produced in every 20g muscles. Creatinine is a kind of minimal molecule that can be filtered out in the kidneys and be excreted out along with the urine. When there are something wrong with kidneys, the function of filtration will be abnormal, so creatinine can be a sign to show kidney functions. When it accumulates in human body, it will become toxins which is harmful for the body. It has close relationship with the amount of muscles, and basically it will not be affected by the food intake or some other extra renal factors. The level of creatinine is mainly based on filtration function of glomeruli when the exogenous creatinine intake is almost stable.
Creatinine can be separated into serum creatinine and urinary creatinine. As we know, after produced from the muscles, creatinine is in the blood. When the blood goes into the kidneys and is filtered through the kidneys, in normal cases, it will be excreted outside of the body along with the urine, so, those part that has been filtered and stay in the urine is called urinary creatinine, and those cannot be smoothly filtered out and stay in the blood is called serum creatinine. When we have some test in the hospital and we get the value of creatinine, it usually refers to the serum creatinine. If there are too much creatinine in the blood, there may be some problems with the kidney filtration function. At the same time, the creatinine in the urine must be less.

Therefore, serum creatinine is a most important value to present the kidney function. If you know what is creatinine and the basic function of kidneys, you will easily know what is serum creatinine as well as urinary creatinine. Any other questions, you are welcome to talk with the consultant online or leave a message to sctvivian@hotmail.com.